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Search Results for " b 27 "

Targets Recommended: Others

10

抑制剂 & 化合物

24

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TP2231	HBcAg [Hepatitis B virus] (18-27)	Others	Others
	HBcAg (core antigen) is a hepatitis B viral protein. It is an indicator of active viral replication; this means the person infected with Hepatitis B can likely transmit the virus on to another person.
T38193L	β-Endorphin (1-27) (human) acetate β-Endorphin (1-27) (human) acetate(76622-84-9 Free base)	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	β-Endorphin (1-27) (human) acetate 存在于大脑垂体和下丘脑中，具有镇痛活性。 β-Endorphin (1-27) (human) acetate 是一种阿片受体激动剂，对 μ-阿片受体和 δ-阿片受体具有较好的亲和力。
TP1692	β-Amyloid (13-27) β-Amyloid 13-27
	β-Amyloid (13-27) is a peptide consisting of amino acid of 13 to 27 of beta amyloid protein. This synthetic peptide consists of amino acids 26 to 40 of beta amyloid protein. It can be used to study the kinetics of beta amyloid formation.
T81866	MAO-B-IN-27	Monoamine Oxidase	Neuroscience
	MAO-B-IN-27（Compound 12c）是一种针对单胺氧化酶B（MAO-B）的有效且选择性的抑制剂，展现出对hMAO-B的显著抑制活性，具有8.9 nM的IC50值，用于帕金森病（PD）研究。
T38193	β-Endorphin (1-27) (human) (trifluoroacetate salt)
	β-Endorphin (1-27) is an endogenous peptide that binds to μ-, δ-, and κ-opioid receptors (Kis = 5.31, 6.17, and 39.82 nM, respectively, in COS-1 cells expressing rat receptors). It binds to rat and mouse brain membrane preparations (IC50s = 1.1 and 5.7 nM, respectively) and induces chemotaxis of human monocytes in vitro when used at a concentration of 1 nM. Intracerebroventricular administration of β-endorphin (1-27) increases the latency to tail withdrawal in response to thermal stimulation in ...
T6338	PHA-680632 PHA 680632,PHA680632	FGFR; PLK; Aurora Kinase	Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors
	PHA-680632 是一种极光激酶抑制剂，对极光激酶 A、B 和C 的IC50值分别为 27、135和 120 nM。它对 FGFR1、FLT3、LCK、PLK1、STLK2 和 VEGFR2/3 的 IC50 高 10 到 200 倍。
T35330	BTK inhibitor 1	BTK	Angiogenesis; Tyrosine Kinase/Adaptors
	BTK inhibitor 1 (Compound 27）是一种BTK 抑制剂（IC50：0.11nM），对hWB 中的B 细胞活化具有抑制作用，IC50为2nM。
T76534	HBV Seq1 aa:18-27
	HBVSeq1 aa:18-27 是乙型肝炎病毒 (HBV) 核心抗原 18-27 肽片段。
T79485	IRAK4-IN-27	IRAK	Immunology/Inflammation; NF-κB
	IRAK4-IN-27（Compound 22）为高效选择性IRAK4抑制剂，具IC50值8.7 nM。该化合物能够抑制含MYD88L265P突变的DLBCL细胞系生长并促进其细胞凋亡(apoptosis)，适用于弥漫大B细胞淋巴瘤(DLBCL)的研究。
T36676	Rineterkib hydrochloride
	Rineterkib hydrochloride (compound B) is an orally active RAF and ERK1/2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly related to the treatment of KRAS-mutant NSCLC, BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer (CRC) and KRAS-mutant ovarian cancer[1]. ERK-IN-1 (compound B) (50, 75 mg/kg, p.o., qd/q2d, 27 days) treatment significantly reduces the tumor volume in the C...

化合物

HBcAg [Hepatitis B virus] (18-27)

Cat.No: TP2231

Target: Others

β-Endorphin (1-27) (human) acetate

Cat.No: T38193L

Synonym: β-Endorphin (1-27) (human) acetate(76622-84-9 Free base)

Target: Opioid Receptor

β-Amyloid (13-27)

Cat.No: TP1692

Synonym: β-Amyloid 13-27

Cat.No: T81866

Target: Monoamine Oxidase

β-Endorphin (1-27) (human) (trifluoroacetate salt)

Cat.No: T38193

Cat.No: T6338

Synonym: PHA 680632,PHA680632

Target: FGFR, PLK, Aurora Kinase

BTK inhibitor 1

Cat.No: T35330

Target: BTK

HBV Seq1 aa:18-27

Cat.No: T76534

Cat.No: T79485

Target: IRAK

Rineterkib hydrochloride

Cat.No: T36676

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04052	IL-17RB Protein, Human, Recombinant (His) interleukin 17 receptor B,IL17RH1,CRL4,IL17B	Human	HEK293
	IL17RB (Interleukin 17 Receptor B) is a Protein Coding gene. IL17RB is the receptor for IL17E, the only member of the IL17 family promoting Th2 reactions. IL17RB is induced on human macrophages by IL4 and enhanced by TGFbeta. Overexpression of IL17RB is associated with poor prognosis and the short survival of breast cancer patients.IL17RB/IL17B signaling triggers a substantial increase in cell growth, proliferation, and migration through the activation of NF-kappaB as well as the up-regulation o...
TMPY-00542	DEFB127 Protein, Human, Recombinant (hFc) DEFB127,defensin beta 127	Human	HEK293
	DEFB127 Protein, Human, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 31.8 kDa. Accession number: A0A2J8MRU9
TMPY-03850	IL-17RB Protein, Human, Recombinant (hFc) IL17RH1,CRL4,interleukin 17 receptor B,IL17B	Human	HEK293
	IL17RB (Interleukin 17 Receptor B) is a Protein Coding gene. IL17RB is the receptor for IL17E, the only member of the IL17 family promoting Th2 reactions. IL17RB is induced on human macrophages by IL4 and enhanced by TGFbeta. Overexpression of IL17RB is associated with poor prognosis and the short survival of breast cancer patients.IL17RB/IL17B signaling triggers a substantial increase in cell growth, proliferation, and migration through the activation of NF-kappaB as well as the up-regulation o...
TMPY-01117	MRAP Protein, Human, Recombinant (hFc) FALP,FGD2,melanocortin 2 receptor accessory protein,GCCD2,	Human	HEK293
	MRAP (Melanocortin 2 Receptor Accessory Protein) is a Protein Coding gene. This gene encodes a melanocortin receptor-interacting protein. It belongs to the MRAP family. MRAP, which contains a single transmembrane domain, has a unique structure, an antiparallel homodimer. MRAP is a single transmembrane domain accessory protein and a critical component of the hypothamo pituitary-adrenal axis. MRAP is highly expressed in the adrenal gland and is essential for adrenocorticotropin hormone (ACTH) rece...
TMPY-02430	BCL6 Protein, Human, Recombinant (aa 1-150, His & Trx) BCL5,ZNF51,B-cell CLL/lymphoma 6,LAZ3,Z	Human	E. coli
	The protein encoded by this gene is an evolutionarily conserved 95-kDa protein containing six C-terminal zinc-finger motifs and an N-terminal POZ domain. It has been reported that BCL-6 is present in DNA-binding complexes in nuclear extracts from various B-cell lines. There are many relationships between non-Hodgkin's lymphoma, diffuse large cell lymphoma and BCL6’s translocations. BCL6 can repress transcription from promoters linked to its DNA target sequence and this activity is dependent upon...
TMPJ-00755	CRYAB Protein, Human, Recombinant (His) α(B)-Crystallin,Alpha(B)-Crystallin,Heat S...	Human	E. coli
	α Crystallin B Chain (CRYAB) is a cytoplasmic protein that belongs to the small heat shock protein (HSP20) family. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. Alpha crystallins acts as molecular chaperones and hold them in in large soluble aggregates. CRYAB is expressed widely in many tissues and or...
TMPY-04059	RAB27B Protein, Human, Recombinant C25KG,RAB27B,RAB27	Human	HEK293
	RAB27B is a member of the Rab family GTPases involved in vesicle trafficking. The Rab27 subfamily consists of Rab27a and Rab27b. The human RAB27B gene is organized in six exons, spanning about 69 kb in the chromosome 18q21.1 region. The Rab27 subfamily of Ras-like GTPases is highly conserved in mammals. There is high degree of conservation in sequence and gene structure between RAB27A and RAB27B genes. Exogenous expression of Rab27b in melanocytes results in melanosomal association as observed f...
TMPY-02128	Serpin B1 Protein, Human, Recombinant (His) HEL57,serpin peptidase inhibitor, clade B ...	Human	Baculovirus-Insect Cells
	SerpinB1 is an endogenous inhibitor of serine proteases recognized for its anti-inflammatory and host-protective properties. Serum SerpinB1 levels are elevated in patients with type 2 diabetes compared with that in healthy subjects and are negatively correlated with serum LDL-C. serpinB1 as an endogenous protein that can potentially be harnessed to enhance functional beta cell mass in patients with diabetes.
TMPY-03813	RAB27B Protein, Human, Recombinant (His) RAB27B, member RAS oncog...	Human	HEK293
	RAB27B is a member of the Rab family GTPases involved in vesicle trafficking. The Rab27 subfamily consists of Rab27a and Rab27b. The human RAB27B gene is organized in six exons, spanning about 69 kb in the chromosome 18q21.1 region. The Rab27 subfamily of Ras-like GTPases is highly conserved in mammals. There is high degree of conservation in sequence and gene structure between RAB27A and RAB27B genes. Exogenous expression of Rab27b in melanocytes results in melanosomal association as observed f...
TMPY-04026	RAB27B Protein, Human, Recombinant (mFc) RAB27B,RAB27	Human	HEK293
	RAB27B is a member of the Rab family GTPases involved in vesicle trafficking. The Rab27 subfamily consists of Rab27a and Rab27b. The human RAB27B gene is organized in six exons, spanning about 69 kb in the chromosome 18q21.1 region. The Rab27 subfamily of Ras-like GTPases is highly conserved in mammals. There is high degree of conservation in sequence and gene structure between RAB27A and RAB27B genes. Exogenous expression of Rab27b in melanocytes results in melanosomal association as observed f...
TMPH-00999	BCL6 Protein, Human, Recombinant (His) BCL-5,B-cell lymphoma 5 protein,B...	Human	E. coli
	BCL6 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-01000	BCL6 Protein, Human, Recombinant ZNF51,LAZ3,ZBTB27,Zinc finger pro...	Human	E. coli
	BCL6 Protein, Human, Recombinant is expressed in E. coli.
TMPH-01457	Human herpesvirus 6B (HHV-6 variant B) (strain Z29) mRNA export factor ICP27 homolog (His & Myc)	HHV-6B	E. coli
	Human herpesvirus 6B (HHV-6 variant B) (strain Z29) mRNA export factor ICP27 homolog (His & Myc) is expressed in E. coli.
TMPJ-00948	Endostatin Protein, Mouse, Recombinant (His) antiangiogenic agent,type XVIII,collagen α-1(XVIII)chain,col...	Mouse	Human Cells
	Endostatin, an endogenous non‑glycosylated inhibitor of endothelial cell proliferation and angiogenesis. It is produced and/or trimmed by metalloproteinases such as MMP‑2 and MMP‑9, and cathepsins S, B and L. The N‑terminal ~27 aa of Endostatin appear to contain the majority of its activity. This region contains zinc binding sites that are thought to be critical for its anti‑endothelial and anti‑tumor effects, as well as multiple cleavage sites that, when used, can modify its activity. Mouse End...
TMPY-00294	EDA2R Protein, Human, Recombinant (hFc) EDA-A2R,EDAA2R,ectodysplasin A2 receptor,XEDAR,TNFRSF27<...	Human	HEK293
	Tumor necrosis factor receptor superfamily member 27, also known as X-linked ectodysplasin-A2 receptor, EDA-A2 receptor, EDA2R, XEDAR and TNFRSF27, is a single-pass type III membrane protein. TNFRSF27 / EDA2R contains threeTNFR-Cys repeats. It is a new member of the tumor necrosis factor receptor family that has been shown to be highly expressed in ectodermal derivatives during embryonic development and binds to ectodysplasin-A2 (EDA-A2). TNFRSF27 / EDA2R is a receptor for EDA isoform A2,...
TMPY-03124	EDA2R Protein, Mouse, Recombinant (hFc) Xedar,TNFRSF27,9430060M22Rik,ectodysplasin A2 recep...	Mouse	HEK293
	Tumor necrosis factor receptor superfamily member 27, also known as X-linked ectodysplasin-A2 receptor, EDA-A2 receptor, EDA2R, XEDAR and TNFRSF27, is a single-pass type III membrane protein. TNFRSF27 / EDA2R contains threeTNFR-Cys repeats. It is a new member of the tumor necrosis factor receptor family that has been shown to be highly expressed in ectodermal derivatives during embryonic development and binds to ectodysplasin-A2 (EDA-A2). TNFRSF27 / EDA2R is a receptor for EDA isoform A2,...
TMPY-01932	EDA2R Protein, Human, Recombinant (His) EDAA2R,ectodysplasin A2 receptor,EDA-A2R,TNFRSF27,X...	Human	HEK293
	Tumor necrosis factor receptor superfamily member 27, also known as X-linked ectodysplasin-A2 receptor, EDA-A2 receptor, EDA2R, XEDAR and TNFRSF27, is a single-pass type III membrane protein. TNFRSF27 / EDA2R contains threeTNFR-Cys repeats. It is a new member of the tumor necrosis factor receptor family that has been shown to be highly expressed in ectodermal derivatives during embryonic development and binds to ectodysplasin-A2 (EDA-A2). TNFRSF27 / EDA2R is a receptor for EDA isoform A2,...
TMPY-00301	EDA2R Protein, Cynomolgus, Recombinant (His) ectodysplasin A2 receptor	Cynomolgus	HEK293
	Tumor necrosis factor receptor superfamily member 27, also known as X-linked ectodysplasin-A2 receptor, EDA-A2 receptor, EDA2R, XEDAR and TNFRSF27, is a single-pass type III membrane protein. TNFRSF27 / EDA2R contains threeTNFR-Cys repeats. It is a new member of the tumor necrosis factor receptor family that has been shown to be highly expressed in ectodermal derivatives during embryonic development and binds to ectodysplasin-A2 (EDA-A2). TNFRSF27 / EDA2R is a receptor for EDA isoform A2,...
TMPY-02935	EDA2R Protein, Rat, Recombinant (hFc) ectodysplasin A2 receptor	Rat	HEK293
	Tumor necrosis factor receptor superfamily member 27, also known as X-linked ectodysplasin-A2 receptor, EDA-A2 receptor, EDA2R, XEDAR and TNFRSF27, is a single-pass type III membrane protein. TNFRSF27 / EDA2R contains threeTNFR-Cys repeats. It is a new member of the tumor necrosis factor receptor family that has been shown to be highly expressed in ectodermal derivatives during embryonic development and binds to ectodysplasin-A2 (EDA-A2). TNFRSF27 / EDA2R is a receptor for EDA isoform A2,...
TMPY-03029	EDA2R Protein, Rat, Recombinant (His) ectodysplasin A2 receptor	Rat	HEK293
	Tumor necrosis factor receptor superfamily member 27, also known as X-linked ectodysplasin-A2 receptor, EDA-A2 receptor, EDA2R, XEDAR and TNFRSF27, is a single-pass type III membrane protein. TNFRSF27 / EDA2R contains threeTNFR-Cys repeats. It is a new member of the tumor necrosis factor receptor family that has been shown to be highly expressed in ectodermal derivatives during embryonic development and binds to ectodysplasin-A2 (EDA-A2). TNFRSF27 / EDA2R is a receptor for EDA isoform A2,...
TMPY-03682	EDA2R Protein, Cynomolgus, Recombinant (hFc) ectodysplasin A2 receptor	Cynomolgus	HEK293
	Tumor necrosis factor receptor superfamily member 27, also known as X-linked ectodysplasin-A2 receptor, EDA-A2 receptor, EDA2R, XEDAR and TNFRSF27, is a single-pass type III membrane protein. TNFRSF27 / EDA2R contains threeTNFR-Cys repeats. It is a new member of the tumor necrosis factor receptor family that has been shown to be highly expressed in ectodermal derivatives during embryonic development and binds to ectodysplasin-A2 (EDA-A2). TNFRSF27 / EDA2R is a receptor for EDA isoform A2,...
TMPK-01413	H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein, Mouse, MHC (His & Avi) H-2K,OVA,MHC,H2-K1	Mouse	HEK293
	Ovalbumin (OVA) has been historically a popular source of such antigens, since OVA can induce both humoral and cellular immune responses based on well-characterised peptide epitopes. The OVA257-264 octapeptide was one of the frst OVA epitopes to be characterised, it has an amino acid sequence SIINFEKL, which is recognised by cytotoxic T lymphocytes. SIINFEKL forms fbrillar assemblies similar to other peptide hydrogels. Te immunoactive properties of this peptide can therefore be related to its se...
TMPK-01412	HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi) SARS-CoV-2 epitope,MHC	Human	HEK293
	HLA-B15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B15:01 were reactive to the immunodominant SARS-CoV-2 S-derived peptide NQKLIANQF, and 100% of the reactive cells displayed memory phenotype.
TMPK-01416	HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated MHC,SARS-CoV-2 epitope	Human	HEK293
	HLA-B15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B15:01 were reactive to the immunodominant SARS-CoV-2 S-derived peptide NQKLIANQF, and 100% of the reactive cells displayed memory phenotype.

重组蛋白

IL-17RB Protein, Human, Recombinant (His)

Cat.No: TMPY-04052

Species: Human

Expression System: HEK293

DEFB127 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00542

Species: Human

Expression System: HEK293

IL-17RB Protein, Human, Recombinant (hFc)

Cat.No: TMPY-03850

Species: Human

Expression System: HEK293

MRAP Protein, Human, Recombinant (hFc)

Cat.No: TMPY-01117

Species: Human

Expression System: HEK293

BCL6 Protein, Human, Recombinant (aa 1-150, His & Trx)

Cat.No: TMPY-02430

Species: Human

Expression System: E. coli

CRYAB Protein, Human, Recombinant (His)

Cat.No: TMPJ-00755

Species: Human

Expression System: E. coli

RAB27B Protein, Human, Recombinant

Cat.No: TMPY-04059

Species: Human

Expression System: HEK293

Serpin B1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02128

Species: Human

Expression System: Baculovirus-Insect Cells

RAB27B Protein, Human, Recombinant (His)

Cat.No: TMPY-03813

Species: Human

Expression System: HEK293

RAB27B Protein, Human, Recombinant (mFc)

Cat.No: TMPY-04026

Species: Human

Expression System: HEK293

BCL6 Protein, Human, Recombinant (His)

Cat.No: TMPH-00999

Species: Human

Expression System: E. coli

BCL6 Protein, Human, Recombinant

Cat.No: TMPH-01000

Species: Human

Expression System: E. coli

Human herpesvirus 6B (HHV-6 variant B) (strain Z29) mRNA export factor ICP27 homolog (His & Myc)

Cat.No: TMPH-01457

Species: HHV-6B

Expression System: E. coli

Endostatin Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00948

Species: Mouse

Expression System: Human Cells

EDA2R Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00294

Species: Human

Expression System: HEK293

EDA2R Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-03124

Species: Mouse

Expression System: HEK293

EDA2R Protein, Human, Recombinant (His)

Cat.No: TMPY-01932

Species: Human

Expression System: HEK293

EDA2R Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-00301

Species: Cynomolgus

Expression System: HEK293

EDA2R Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-02935

Species: Rat

Expression System: HEK293

EDA2R Protein, Rat, Recombinant (His)

Cat.No: TMPY-03029

Species: Rat

Expression System: HEK293

EDA2R Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPY-03682

Species: Cynomolgus

Expression System: HEK293

H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein, Mouse, MHC (His & Avi)

Cat.No: TMPK-01413

Species: Mouse

Expression System: HEK293

HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01412

Species: Human

Expression System: HEK293

HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01416

Species: Human

Expression System: HEK293

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